Incidence Of Micro-Albuminura In Diabetes Mellitus Type 2; A Prospective Study In Association With Age, Sex, Weight And Creatinine Clearance In Weston Up (Hapur)

Micro-albuminuria refers to the excretion of albumin in the urine at a rate that exceeds normal limits and is considered to be a earliest marker of diabetic nephropathy. If left untreated it will eventually lead to end stage renal disease (ESRD). The current study was conducted to establish the prevalence of micro-albuminuria in a sequential sample of diabetic patients attending hospital and OPD Clinic to determine its relationship with known and putative risk factors, to identify micro and normo-albuminuric patients in their sample for subsequent comparison in different age, sex, weight and creatinine clearance of the microand normoalbuminuric patients, This crossectional analytical study was conducted in one hundred patients at Sarswathi Institute of Medical Sciences, Anwarpur Hapur U.P. Patients having diabetes mellitus in deferent age group ranging from 30 to 70 years were selected. Data was analyzed by SPSS software. Micro-albuminuria was observed in 35% in patients with type 2 diabetes mellitus. It was observed that 65% patients were free from any type of albuminuria. Also micro-albuminuria was present in 10% of the patients less than 50 yrs of age while 15% of the patients more than 5o yrs of age were having micro-albuminuria. There was a statistically significant correlation of micro-albuminuria with duration of diabetes. Incidence of micro-albuminuria increases with age as well as increased duration of diabetes mellitus. Our study shows that only 5% patients developed macro-albuminuria. Glycosylated haemoglobin and fasting plasma glucose was significantly raised among all these patients.